gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The antibody binds CD3 on T cells to activate and redirect them; the activated T cells then kill antigen-positive target cells (e.g., via perforin/granzyme), not the CD3+ T cells themselves.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Epsilon chain of the TCR-CD3 complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT04864522
disease_id_num_tar_ref
1488
drug_id_num_tar_ref
4025