gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG binds CD3 on T cells and induces complement-dependent lysis and Fc-mediated ADCC/phagocytosis, and can trigger apoptosis, leading to depletion of CD3+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Representative CD3 subunit (epsilon) within TCR-CD3 complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06334367
disease_id_num_tar_ref
1648
drug_id_num_tar_ref
4462