gene_symbol
CD8A
hgnc_id
HGNC:1706
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG antibodies bind CD8 on T cells, triggering complement-dependent lysis and Fc-mediated effector killing (ADCC/phagocytosis), and can also induce apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD8 alpha chain (representative)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06334367
disease_id_num_tar_ref
1648
drug_id_num_tar_ref
4462