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gene_symbol
ITGB2
hgnc_id
HGNC:6155
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG contains polyclonal antibodies that bind T‑cell surface antigens including LFA‑1 (CD18), leading to complement-dependent lysis and Fc‑mediated ADCC/apoptosis of the bound cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Integrin beta 2 chain
trial_id_tar_ref
nct_id_tar_ref
NCT06334367
disease_id_num_tar_ref
1648
drug_id_num_tar_ref
4462