gene_symbol
HLA-DRA
hgnc_id
HGNC:4947
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG contains antibodies that bind HLA-DR on leukocytes, triggering complement-dependent lysis and Fc-mediated ADCC/phagocytosis, and can induce apoptosis via receptor crosslinking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class II alpha chain (representative)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06334367
disease_id_num_tar_ref
1648
drug_id_num_tar_ref
4462