gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Epcoritamab bridges CD3+ T cells to CD20+ cells, forming an immune synapse that activates TCR/CD3 signaling and induces perforin/granzyme-mediated T‑cell cytotoxicity against CD20-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06458439
disease_id_num_tar_ref
186
drug_id_num_tar_ref
507