gene_symbol
ITGAL
hgnc_id
HGNC:6148
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG contains antibodies that bind CD11a (LFA-1) on T cells and deplete them via complement-dependent lysis and Fc-mediated effector functions (ADCC by NK cells and phagocytosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Integrin alpha-L; adhesion molecule
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05508009
disease_id_num_tar_ref
1653
drug_id_num_tar_ref
4475