gene_symbol
HLA-DRA
hgnc_id
HGNC:4947
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
ATG does not target HLA‑DR; it binds multiple T‑cell antigens and depletes T cells via complement-dependent cytotoxicity and Fc-mediated ADCC/phagocytosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05508009
disease_id_num_tar_ref
1653
drug_id_num_tar_ref
4475