gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Afucosylated anti-BCMA IgG1 opsonizes BCMA+ cells and engages Fcγ receptors on NK cells and macrophages to mediate ADCC and ADCP; may also trigger apoptosis via BCMA ligation.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05714839
disease_id_num_tar_ref
1658
drug_id_num_tar_ref
4483