gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Antibody binds gp120 on Env-expressing (HIV‑infected) cells and engages Fcγ receptors on effector cells to trigger ADCC/ADCP (± complement), leading to killing of the target cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD4-binding site (CD4bs) epitope on gp120
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05959707
disease_id_num_tar_ref
195
drug_id_num_tar_ref
528