gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognizing CD20 bind the antigen and, upon CAR signaling, directly lyse CD20+ cells via perforin/granzyme release and death-receptor pathways (MHC-independent).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Some CAR T products target CD20; MHC-independent recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05852717
disease_id_num_tar_ref
1825
drug_id_num_tar_ref
4882