gene_symbol
UNKNOWN
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine binds receptors on antigen-presenting cells to deliver HPV16 E6/E7 for cross-presentation and APC activation, inducing HPV16-specific cytotoxic T cells that kill HPV16 E6/E7–positive tumor cells, not the APCs expressing the targeted receptor.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Targeted by APC-binding unit of the vaccine to enhance uptake and cross-presentation
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06099418
disease_id_num_tar_ref
1948
drug_id_num_tar_ref
5217