gene_symbol
IL2RA
hgnc_id
HGNC:6008
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG antibodies bind CD25 on T cells and trigger complement-dependent cytotoxicity and Fc-mediated ADCC/phagocytosis, leading to lysis and apoptosis of the bound cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05973734
disease_id_num_tar_ref
2004
drug_id_num_tar_ref
5370