gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The IgG1 antibody binds Env on infected cells and engages Fcγ receptor–bearing effector cells to mediate ADCC/ADCP (and potentially complement activation), resulting in immune-mediated killing/clearance of the target cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Glycan-dependent epitope centered on N332 on gp120 V3 region
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06508749
disease_id_num_tar_ref
2055
drug_id_num_tar_ref
5498