gene_symbol
TNFSF7
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-engineered Vδ1 γδ T cells bind CD70 on target cells, activate, and kill CD70+ cells via perforin/granzyme-mediated cytolysis (with supporting cytokine/Fas–FasL pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-associated antigen on ccRCC targeted by CAR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06480565
disease_id_num_tar_ref
2147
drug_id_num_tar_ref
5727