gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CMV gB on target cells and, via MHC‑independent CAR signaling, release perforin/granzymes (and cytotoxic cytokines) to induce lysis/apoptosis of gB-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Viral (HCMV) envelope fusion glycoprotein; encoded by UL55
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06849921
disease_id_num_tar_ref
215
drug_id_num_tar_ref
604