gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Blinatumomab bridges CD3 on T cells to CD19 on target cells, activating T cells to deliver perforin/granzyme-mediated killing of CD19+ cells (MHC-independent).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05848687
disease_id_num_tar_ref
2161
drug_id_num_tar_ref
5779