gene_symbol
TNFSF7
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD70 CAR T cells bind CD70 on target cells and induce cytolysis via T‑cell degranulation (perforin/granzyme–mediated apoptosis), with possible death‑receptor and cytokine effects.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
membrane-bound, tumor cell surface expression
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05947487
disease_id_num_tar_ref
2212
drug_id_num_tar_ref
5921