gene_symbol
TRAC
hgnc_id
HGNC:12029
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal anti-thymocyte IgG binds TCR/CD3 (including TCRα) on T cells and induces complement-mediated lysis and Fc-dependent ADCC; cross-linking can also trigger apoptosis, depleting TCRα-expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TCRαβ complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06872333
disease_id_num_tar_ref
225
drug_id_num_tar_ref
630