gene_symbol
PTK7
hgnc_id
HGNC:9618
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ADC binds PTK7 on tumor cells, is internalized, and releases an intracellular cytotoxic payload that kills the PTK7-expressing cell.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface receptor; catalytically inactive (pseudokinase)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06752681
disease_id_num_tar_ref
2287
drug_id_num_tar_ref
6121