gene_symbol
CD5
hgnc_id
HGNC:1685
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG antibodies bind CD5 on T cells and deplete them via complement-dependent cytotoxicity and Fc-mediated ADCC, with additional apoptosis induction.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06872333
disease_id_num_tar_ref
225
drug_id_num_tar_ref
630