gene_symbol
ITGB2
hgnc_id
HGNC:6155
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal antibodies in ATG bind CD18 on T cells, triggering complement-dependent lysis, antibody-dependent cellular cytotoxicity, and apoptosis to deplete target-expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
LFA-1 integrin beta subunit
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06872333
disease_id_num_tar_ref
225
drug_id_num_tar_ref
630