gene_symbol
HLA-C
hgnc_id
HGNC:4933
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Thymoglobulin does not target HLA-C; it binds multiple T-cell antigens (e.g., CD2/CD3/CD4/CD8) and depletes T cells via complement-dependent cytotoxicity, ADCC, and apoptosis.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class I heavy chain
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06872333
disease_id_num_tar_ref
225
drug_id_num_tar_ref
630