gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells bind the antigen and trigger T-cell effector cytotoxicity, primarily perforin/granzyme-mediated lysis (and related apoptosis) of antigen-positive tumor cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Dual-target CAR-T; antigen identity not disclosed in NCT06645301/NCI Thesaurus
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06645301
disease_id_num_tar_ref
2489
drug_id_num_tar_ref
6652