gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR binding to CD19 activates the engineered T cell to kill target cells via perforin/granzyme-mediated cytolysis (and Fas–FasL), MHC-independently.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Extracellular domain epitope on B-lineage cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06481228
disease_id_num_tar_ref
2502
drug_id_num_tar_ref
6687