gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The DC vaccine primes tumor-specific T cells; CD4+ T cells recognizing neoantigen–HLA class II (and CD8+ CTLs via cross-priming) mediate killing of antigen-bearing tumor cells via perforin/granzyme and Fas–FasL–induced apoptosis.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–MHC II complexes recognized by CD4+ T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06043232
disease_id_num_tar_ref
2555
drug_id_num_tar_ref
6825