gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
rATG contains antibodies to CD3 that bind CD3E on T cells and deplete them via complement-dependent cytotoxicity and Fc-mediated effector functions (ADCC/phagocytosis), with additional apoptosis upon cross-linking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TCR/CD3 complex component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06158828
disease_id_num_tar_ref
242
drug_id_num_tar_ref
683