gene_symbol
CD7
hgnc_id
HGNC:1695
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal rabbit IgG in rATG binds CD7 on T cells; Fc activates complement (CDC) and engages Fcγ receptors for ADCC/phagocytosis, and can trigger apoptosis, depleting CD7+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06158828
disease_id_num_tar_ref
242
drug_id_num_tar_ref
683