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gene_symbol
ITGAL
hgnc_id
HGNC:6148
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
rATG contains antibodies that bind T‑cell antigens including CD11a, opsonizing these cells and inducing complement-dependent lysis and Fc receptor–mediated ADCC/phagocytosis, leading to apoptosis and depletion.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Integrin LFA-1 alpha chain
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06158828
disease_id_num_tar_ref
242
drug_id_num_tar_ref
683