gene_symbol
HLA-A
hgnc_id
HGNC:4931
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
rATG contains antibodies that bind HLA-A on target cells and mediate complement-dependent cytotoxicity and Fc-dependent ADCC/phagocytosis (and apoptosis), directly depleting those cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HLA class I
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06158828
disease_id_num_tar_ref
242
drug_id_num_tar_ref
683