gene_symbol
CD8A
hgnc_id
HGNC:1706
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG binds CD8 (alpha) and other T‑cell antigens; bound antibody induces complement-dependent cytotoxicity and Fc receptor–mediated ADCC/phagocytosis, depleting CD8+ T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06378060
disease_id_num_tar_ref
2749
drug_id_num_tar_ref
7328