gene_symbol
HLA-DRA
hgnc_id
HGNC:4947
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
rATG contains antibodies that bind HLA-DR on the cell surface and trigger complement-dependent lysis and Fc-mediated ADCC/phagocytosis, causing apoptosis/lysis of the targeted cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HLA class II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06158828
disease_id_num_tar_ref
242
drug_id_num_tar_ref
683