gene_symbol
HLA-DRA
hgnc_id
HGNC:4947
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
ATG does not target HLA-DR; it binds multiple T-cell antigens and depletes T cells via complement-dependent lysis and Fc-mediated ADCC/phagocytosis, not by recognizing HLA-DR-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06378060
disease_id_num_tar_ref
2749
drug_id_num_tar_ref
7328