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gene_symbol
HLA-A
hgnc_id
HGNC:4931
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
ATG depletes T cells by binding T-cell antigens and inducing complement-dependent lysis and Fc-mediated ADCC/phagocytosis; it does not specifically target HLA class I heavy chain.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
represents HLA-A/B/C class I targets
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06378060
disease_id_num_tar_ref
2749
drug_id_num_tar_ref
7328