gene_symbol
CD44
hgnc_id
HGNC:1681
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD44v6-binding antibody delivers 177Lu beta radiation to target cells, inducing DNA double‑strand breaks and tumor cell death (with cross‑fire to nearby cells).
enzyme_product
Off
epitope
On
variant
On
isoform
On
hla_specific
Off
gated
Off
other_modifier
Cell-surface splice-variant epitope in variable exon v6 region
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06639191
disease_id_num_tar_ref
3023
drug_id_num_tar_ref
8114