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gene_symbol
IL2RB
hgnc_id
HGNC:6009
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CD122+ T and NK cells are stimulated by IL-15/IL-15Rα transpresentation from the dendritic-cell vaccine, expanding and enhancing their cytotoxicity; these effectors then kill WT1-expressing tumor cells, not the CD122-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Receptor engaged by transpresented IL-15/IL15RA on T and NK cells
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05964361
disease_id_num_tar_ref
3075
drug_id_num_tar_ref
8242