gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific antibody binds CD3 on T cells to activate and redirect them to kill CD19+ B cells via cytolytic synapse (perforin/granzyme); CD3+ T cells themselves are not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD3 complex on T cells (subunit not specified); part of TCR/CD3 complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06565689
disease_id_num_tar_ref
3144
drug_id_num_tar_ref
8440