gene_symbol
PSCA
hgnc_id
HGNC:9500
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
PSCA-specific CAR-engineered gamma delta T cells bind PSCA on tumor cells and directly lyse them via immunologic synapse formation and perforin/granzyme-mediated cytotoxicity (MHC-independent).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
GPI-anchored cell-surface glycoprotein; MHC-independent CAR binding
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06193486
disease_id_num_tar_ref
3200
drug_id_num_tar_ref
8580