gene_symbol
CD6
hgnc_id
HGNC:1691
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
rATG antibodies bind CD6 on T cells and mediate complement-dependent lysis and Fc-dependent ADCC, with additional apoptosis, leading to depletion of CD6+ lymphocytes.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05806749
disease_id_num_tar_ref
3274
drug_id_num_tar_ref
8793