gene_symbol
IL2RA
hgnc_id
HGNC:6008
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
rATG contains antibodies that bind CD25 on T cells; Fc engagement activates complement (CDC) and recruits effector cells for ADCC, also inducing apoptosis, thereby depleting CD25+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Alpha chain of high-affinity IL-2 receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05806749
disease_id_num_tar_ref
3274
drug_id_num_tar_ref
8793