gene_symbol
ICAM1
hgnc_id
HGNC:5344
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
rATG contains antibodies that bind ICAM1 on cells, leading to complement-dependent lysis and Fc-mediated ADCC, and can also induce apoptosis of the bound ICAM1+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Ligand for LFA-1
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05806749
disease_id_num_tar_ref
3274
drug_id_num_tar_ref
8793