gene_symbol
HLA-DRA
hgnc_id
HGNC:4947
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal rATG antibodies can bind HLA‑DR on leukocytes and trigger complement-dependent cytotoxicity and Fc-mediated ADCC/apoptosis, depleting HLA‑DR–expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Class II heterodimer with HLA-DRB chains
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05806749
disease_id_num_tar_ref
3274
drug_id_num_tar_ref
8793