gene_symbol
ITGAL
hgnc_id
HGNC:6148
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG antibodies bind CD11a on T cells and induce complement-dependent lysis and Fc-mediated ADCC, with additional apoptosis, directly depleting CD11a+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Integrin alpha-L
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06305286
disease_id_num_tar_ref
288
drug_id_num_tar_ref
814