gene_symbol
HLA-A
hgnc_id
HGNC:4931
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
ATG binds multiple T‑cell surface antigens (e.g., CD2/CD3/CD4/CD8) and depletes T cells via complement-dependent cytotoxicity and Fc-mediated ADCC/apoptosis; HLA-A expression itself is not the target of killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class I heavy chain
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06305286
disease_id_num_tar_ref
288
drug_id_num_tar_ref
814