gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The DC vaccine primes/expands EBV-specific CD8+ T cells, which recognize EBV peptide–HLA I complexes on target cells and kill them via perforin/granzyme (and Fas–FasL) cytotoxicity.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented on HLA-A/B/C by autologous dendritic cells to CD8+ T cells (peptide–MHC I complexes)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05635591
disease_id_num_tar_ref
3423
drug_id_num_tar_ref
9248