gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Antibody binds Env gp120 on infected cell surfaces; its IgG1 Fc engages Fcγ receptors on NK cells/macrophages to trigger ADCC/ADCP (and potentially complement), killing the Env-expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Glycan-dependent (oligomannose) epitope; requires N332 V3 glycan patch
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06071767
disease_id_num_tar_ref
3438
drug_id_num_tar_ref
9295