gene_symbol
ROR1
hgnc_id
HGNC:10256
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
EMB-07 links CD3 on T cells to ROR1 on tumor cells, activating CTLs to kill ROR1+ cells via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
tumor-associated cell-surface receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05607498
disease_id_num_tar_ref
3459
drug_id_num_tar_ref
9361