gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
EMB-07 crosslinks CD3 on T cells with ROR1 on tumor cells, activating T cells to kill ROR1-positive cancer cells via perforin/granzyme; CD3+ T cells themselves are not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
component of the T-cell receptor complex on T cells; specific CD3 subunit not specified
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05607498
disease_id_num_tar_ref
3459
drug_id_num_tar_ref
9361