gene_symbol
UNKNOWN
binding_type
other
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Aztreonam binds PBP3 (FtsI) in Gram-negative bacteria, inhibiting peptidoglycan crosslinking and cell-wall synthesis, leading to loss of wall integrity and osmotic lysis (bactericidal).
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Gram-negative bacterial D,D-transpeptidase involved in septal peptidoglycan synthesis
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05777603
disease_id_num_tar_ref
3486
drug_id_num_tar_ref
9439