gene_symbol
FCGR3A
hgnc_id
HGNC:3619
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The antibody’s Fc binds CD16A on NK cells to trigger ADCC against HIV Env–coated/infected cells; CD16A-expressing cells themselves are not targeted or killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Fc-mediated ADCC on NK cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05769569
disease_id_num_tar_ref
3531
drug_id_num_tar_ref
9565